Endocrine Abstracts

Introduction: LDL cholesterol (LDL-C) is a major risk factor for atherosclerosis. The Friedewald formula (FF) is limited by hypertriglyceridaemia. We aimed to correlate serum LDL-C measured by direct assay with serum LDL-C estimated by several formulas: Friedewald (FF): LDL-C=CT-HDL−TG/5; Tsai (TsaiF): LDL-C=TC-HDL−TG/8 (TG/8 represents very-LDL-C); DeLong (DeLongF): LDL-C=TC-HDL−TG×0.16 and Chen (ChenF): LDL-C=non-HDL-cholesterol×0.9−TG×...

Introduction: Vitamin D is a hormone that acts through the Vitamin D receptor (VDR) not only on the skeletal system but on a great number of target tissues, including thyroid gland. In recent years the association of vitamin D with autoimmune thyroid diseases (AITD), has been suggested.VDR gene polymorphisms had been associated with an increased risk of AITD. In addition a recent meta-analysis showed that AITD patients had lower level of 25-hydroxyvitami...

Introduction: The assessment of pituitary function is often achieved by means of sequential determinations (pool) of hormone levels such as prolactin and gonadotrophins. For the determination of prolactin levels the guidelines of the Endocrine Society are clear in recommending a single sample determination.Objective: To evaluate differences between single sample and pool (0′, 20′ and 60′) determinations for assessing prolactin, FSH and ...

Introduction: The course of type 2 diabetes mellitus (DM) is insidious and, before its development, other glucose homeostasis abnormalities can be detected: impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and elevation of HbA1c.Aims: To compare the prevalence of glucose homeostasis abnormalities in obese patients, using diagnostic criteria of American Diabetes Association (ADA) 2009, ADA 2010 and International Diabetes Federation (IDF) 2...